Is Modafinil safe during pregnancy?

Modafinil is used for the treatment of Narcolepsy. It may be prescribed to treat shift work sleep disorder or obstructive sleep apnea as well. Some people believe that Modafinil can provide cognitive benefits, and that’s an off-label use for it, although there’s not much evidence to support this. Modafinil's side effects include anxiety, headache, nausea, and sleep disturbances. Serious side effects can include hallucinations and allergic reactions. Modafinil is a schedule IV controlled substance in the U.S. since there is a slight risk of addiction. It is similar to some other stimulant drugs that are addictive, but there are differences as well. Modafinil can have mild mood-lifting properties. However, despite this, there are quite a few reports of people misusing or becoming addicted to Modafinil.

Modafinil is primarily prescribed for the treatment of Narcolepsy. Untreated Narcolepsy while pregnant will make the woman gain more weight than what’s considered healthy. This will increase the risk of complications like impaired glucose metabolism and anemia. Despite these complications connected to Narcolepsy, pregnant women are often very cautious about the medications they can take during this time. So, the question is can you take Modafinil while carrying a child? The answer can be confusing for pregnant women, as it is for so many other medications. Modafinil may be safe during pregnancy, but it can also be unsafe.

The FDA categorizes medicines and other substances based on their perceived safety or risks during pregnancy. The category determinations are based on available research from both animal and human-controlled studies. Few controlled human studies involve the observation of the effects of medicines during pregnancy, however. Human studies during pregnancy can be unethical and dangerous. Hence most human studies during pregnancy are observational studies. For example, no controls are used, but researchers might ask pregnant women to respond as to whether or not they’ve used a certain medicine. The total substances are categorized into three types. They are Category A, B, and C. Category A is considered the safest during pregnancy. Category B substances are fairly safe. Most of the drugs fall into category C drugs. Category C drugs are those that may have shown some indication of harm to a fetus in animal studies, and there is a lack of well-controlled human studies. When a drug is in category C, a doctor is required to assess the benefits it can deliver, compared to the risks it will bring. Then, a decision can be made as to whether a pregnant woman should continue using the medication or not. Modafinil is considered a Category C drug during pregnancy.

Role in birth defects?

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